Comparison of Two Methods of Capillary Sampling in Blood Pre-Donation Anemia Screening in Brazil

Autor: Cristina Rabelo Flor, André de Oliveira Baldoni, Sheila de Oliveira Garcia Mateos, Ester Cerdeira Sabino, Cláudia Di Lorenzo Oliveira
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Hematology Reports, Vol 15, Iss 2, Pp 298-304 (2023)
Druh dokumentu: article
ISSN: 2038-8330
DOI: 10.3390/hematolrep15020030
Popis: Background: The laboratory tests most used by blood banks to diagnose anemia are the hemoglobin (Hb) and microhematocrit (Hct) tests, measured from capillary samples. Objective: To analyze the two capillary screening methods for pre-donation anemia by comparing their agreement in diagnosing anemia. Method: A cross-sectional study in a population of 15,521 blood donation candidates for whom information was available on Hb and Hct, performed from capillary blood samples. Hb was determined using the HemoCue® test and Hct by the centrifugation method. The Kappa coefficient was calculated to assess the agreement between the methods. Pearson’s correlation tests and gender-adjusted linear regression were used to assess the change in the response variable (Hb) as a function of the explanatory variable (Hct). Results: The majority of the study population were men (70.4%), aged between 18 and 44 years (72.1%), who declared themselves white or mixed skin color (85.6%), and had undergone at least 11 years of complete education (72.4%). The Kappa coefficient found was 92.7 and 99.2 for women and men, respectively. Pearson’s correlation showed a correlation coefficient of 0.98 and the linear regression graph showed an adequate relationship between the tests with R2 = 0.97. Conclusions: Comparing the Hb and Hct capillary tests, it was found that Hct can be safely used to screen for anemia in pre-blood donation.
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