| Autor: |
Zisis Tsouris, Antonios Provatas, Christos Bakirtzis, Athina-Maria Aloizou, Vasileios Siokas, Vana Tsimourtou, Nikolaos Grigoriadis, Georgios M. Hadjigeorgiou, Efthimios Dardiotis |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Neurology International, Vol 14, Iss 4, Pp 991-996 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2035-8377 |
| DOI: |
10.3390/neurolint14040078 |
| Popis: |
(1) Introduction: There have been numerous reports on the neuroinvasive competence of SARS-CoV-2. Here, we present a case with anti-MOG positive bilateral optic neuritis and brainstem encephalitis secondary to COVID-19 infection. Additionally, we present a review of the current literature regarding the manifestation of anti-MOG positive optic neuritis as well as anti-MOG positive encephalitis after COVID-19 infection. (2) Case Report: A 59-year-old female patient, with a recent history of COVID-19 infection, presented a progressive reduction of visual acuity and bilateral retrobulbar pain for the last 20 days. An ophthalmological examination revealed a decreased visual acuity (counting fingers) and a bilateral papilledema. An MRI scan of the brain revealed a mild thickening of the bilateral optic nerves and high-intensity lesions in the medial and right lateral pons. A high titer of IgG and IgM antibodies against SARS-CoV-2 in serum and antibodies against myelin oligodendrocyte glycoprotein (anti-MOG) in serum and CSF were revealed. The diagnosis of anti-MOG brainstem encephalitis and optic neuritis was set. (3) Conclusions: The history of COVID-19 infection should raise awareness about these autoimmune and infection-triggered diseases, such as anti-MOG antibody disease. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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