Pathophysiology of Post-COVID syndromes: a new perspective

Autor:	Gaber El-Saber Batiha, Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Nermeen N. Welson
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	COVID-19 Post-COVID syndrome Mast cell activation syndrome Pathogenesis Infectious and parasitic diseases RC109-216
Zdroj:	Virology Journal, Vol 19, Iss 1, Pp 1-20 (2022)
Druh dokumentu:	article
ISSN:	1743-422X
DOI:	10.1186/s12985-022-01891-2
Popis:	Key summary points Post-COVID (PCS) syndrome may progress in association with the development of mast cell activation syndrome (MCAS). High D-dimer levels and blood urea nitrogen were observed to be risk factors associated with pulmonary dysfunction in COVID-19 survivors 3 months post-hospital discharge with the development of PCS. Persistence of inflammatory reactions, autoimmune mimicry, and reactivation of pathogens together with host microbiome alterations may contribute to the development of PCS. MCAS is treated by antihistamines, inhibition of synthesis of mediators, inhibition of mediator release, and inhibition of degranulation of mast cells.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/36bcbd2fd1b04a01b8b7148ea2be214c Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.