Cerebral venous sinus thrombosis-associated hemorrhage in vaccine-induced immune thrombotic thrombocytopenia: Catastrophic outcome if delayed diagnosis and treatment

Autor:	Chee-Tat Lam, Kuan-Yu Lin, Ming-Chien Kao, Ming-Cheng Tsai
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	anti-platelet factor 4 antibodies cerebral venous thrombosis vaccine-induced immune thrombotic thrombocytopenia Surgery RD1-811
Zdroj:	Formosan Journal of Surgery, Vol 55, Iss 4, Pp 158-160 (2022)
Druh dokumentu:	article
ISSN:	1682-606X
DOI:	10.4103/fjs.fjs_236_21
Popis:	The authors reported the clinical course of a 58-year-old female suffering from cerebral venous sinus thrombosis associated with hemorrhage after the ChAdOx1 nCov-19 vaccination. Emergent decompressive craniectomy was performed, and aggressive blood transfusion was given. Nevertheless, progressive intracerebral hemorrhage and thrombocytopenia developed. A delayed diagnosis was made on a rare complication of vaccine-induced immune thrombotic thrombocytopenia (VITT) with a positive result of anti-platelet factor 4 antibodies (PF4 Ab). The patient died 4 days postoperative due to brainstem failure.
Databáze:	Directory of Open Access Journals
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