18F-FDG PET/CT imaging findings in anaplastic large cell lymphoma, a rare subtype of lymphoma
| Autor: | Yanping Jiang, Lijuan Wang, Wenlan Zhou, Jiamei Gu, Ying Tian, Ye Dong, Lilan Fu, Hu-bing Wu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Anaplastic large cell lymphoma (ALCL)
Anaplastic lymphoma kinase (ALK) Diffuse large B cell lymphoma (DLBCL) Positron emission tomography (PET) Computed tomography (CT) Deoxyglucose Medical physics. Medical radiology. Nuclear medicine R895-920 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
| Zdroj: | Cancer Imaging, Vol 20, Iss 1, Pp 1-9 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1470-7330 |
| DOI: | 10.1186/s40644-019-0278-5 |
| Popis: | Abstract Objective To investigate the 18F-FDG PET/CT imaging manifestations for anaplastic large cell lymphoma (ALCL), a rare subtype of T/NK cell lymphoma. Methods Fifty patients with ALCL, including 32 anaplastic lymphoma kinase (ALK)-positive patients and 18 ALK-negative patients, were enrolled. The positive detection, maximal standardized uptake value (SUVmax), and distribution of nodal and extranodal involvement were recorded and analysed. Fifty patients with diffuse large B cell lymphoma (DLBCL) were collected as a control group. Results ALCL lesions were demonstrated to be 18F-FDG-avid tumours with a mean SUVmax of 19.4 ± 12.6. Most (76%) ALCL patients presented with stage III-IV disease, and nodal and extranodal involvement occurred in 74.0 and 72.0% of the patients, respectively. ALCL and DLBCL showed many similarities in tumour stage, 18F-FDG uptake and tumour involvement (P > 0.05), although the preferred extranodal organs of involvement (bone and the gastrointestinal tract, respectively) were different (P |
| Databáze: | Directory of Open Access Journals |
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