Recurrence rates and associated risk factors after conservative surgery for adenomyosis: a retrospective study

Autor: Keji Lu, Guangzheng Zhong, Bingrong Lian, Xiaozhu Zhong, Meiqing Xie, Yingchen Wu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Women's Health, Vol 24, Iss 1, Pp 1-8 (2024)
Druh dokumentu: article
ISSN: 1472-6874
DOI: 10.1186/s12905-024-03457-6
Popis: Abstract Background Conservative surgery for adenomyosis has been shown to be effective. However, risk factors for postoperative recurrence have yet to be clarified. In this study, we aimed to determine the recurrence rate after conservative surgery for adenomyosis and identify the risk factors for recurrence. Methods This retrospective study was conducted in a tertiary hospital. Patients who underwent conservative surgery for adenomyosis between January 2013 and April 2023 were identified. Eligible patients were assigned to either the recurrent or non-recurrent group. Continuous and categorical variables were compared between the two groups using the Mann–Whitney U test or chi-squared test. Risk factors for recurrence were identified by Cox proportional risk analysis. Results Data for 133 eligible patients who underwent conservative surgery for adenomyosis were analyzed. The mean follow-up duration was 52 months. The recurrence rate after conservative surgery was 39.1% (52/133). Cox proportional risk analysis identified adenomyosis involving the posterior uterine wall (hazard ratio [HR] 6.505, P = 0.018), two or more adenomyotic lesions (HR 6.310, P = 0.030), laparotomy (HR 2.490, P = 0.029), and concomitant endometriosis (HR 2.313, P = 0.036) to be risk factors for recurrence after conservative surgery. Postoperative combined progestogen therapy (HR 0.126, P
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