In vitro anti-oxidant, anti-inflammatory, anti-bacterial, and cytotoxic effects of extracted colorants from two species of dragon fruit (Hylocereus spp.)

Autor: Md. Ashaduzzaman Nur, M. Rasel Uddin, Nigar Sultana Meghla, M. Jashim Uddin, M. Ziaul Amin
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Food Chemistry Advances, Vol 2, Iss , Pp 100318- (2023)
Druh dokumentu: article
ISSN: 2772-753X
DOI: 10.1016/j.focha.2023.100318
Popis: To evaluate the medicinal value of natural colorants derived from dragon fruit, this research measures the antioxidant, anti-inflammatory, antibacterial, and cytotoxic activities of extracted colorant from two species (Hylocereus polyrhizus and Hylocereus undatus) of dragon fruit at different concentrations. The cold extraction method was used for extraction. Anti-oxidant, anti-inflammatory, antibacterial, and cytotoxic assay were measured using free radical scavenging, denaturation, and hemolytic inhibitory, disk diffusion, liquid microdilution assay, brine shrimp lethality and 3-(4,5-dimethyl-2- thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assays, respectively. The aqueous extract showed high levels of phytochemicals (phenolics and flavonoids) in contrast to the other two (ethanol and ethyl acetate) extracts. Aqueous extract colorants exhibited better antioxidant and anti-inflammation activity than other two extracts (p
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