Drug reaction with eosinophilia and systemic symptoms (DRESS) caused by sulfasalazine: a case report and literature review

Autor: A. S. Fedorov, Yu. O. Savelyeva, Yu. Yu. Grabovetskay, L. A. Rudyuk, E. M. Kuchinskaya, M. M. Kostik
Jazyk: ruština
Rok vydání: 2024
Předmět:
Zdroj: Современная ревматология, Vol 18, Iss 2, Pp 81-87 (2024)
Druh dokumentu: article
ISSN: 1996-7012
2310-158X
DOI: 10.14412/1996-7012-2024-2-81-87
Popis: Drug-induced hypersensitivity syndrome (DIHS) or drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare, potentially fatal systemic reaction characterized by multiorgan damage involving the liver, hematopoietic system and skin, and heterogeneous manifestations of fever, rash, lymphadenopathy and eosinophilia with unpredictable course.We describe a 41-year-old female patient who developed DRESS syndrome after taking sulfasalazine prescribed for non-radiographic axial spondyloarthritis. Treatment with intravenous and then oral glucocorticoids was effective. A review of the literature on this topic is presented.
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