| Autor: |
Gitte Zels, Karen Van Baelen, Maxim De Schepper, Kristien Borremans, Tatjana Geukens, Edoardo Isnaldi, Hava Izci, Sophia Leduc, Amena Mahdami, Marion Maetens, Ha Linh Nguyen, Anirudh Pabba, François Richard, Josephine Van Cauwenberge, Ann Smeets, Ines Nevelsteen, Patrick Neven, Hans Wildiers, Wouter Van Den Bogaert, Giuseppe Floris, Christine Desmedt |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Breast, Vol 75, Iss , Pp 103732- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1532-3080 |
| DOI: |
10.1016/j.breast.2024.103732 |
| Popis: |
Primary tumors with a mixed invasive breast carcinoma of no-special type (IBC-NST) and invasive lobular cancer (ILC) histology are present in approximately five percent of all patients with breast cancer and are understudied at the metastatic level. Here, we characterized the histology of metastases from two patients with primary mixed IBC-NST/ILC from the postmortem tissue donation program UPTIDER (NCT04531696). The 14 and 43 metastatic lesions collected at autopsy had morphological features and E-cadherin staining patterns consistent with pure ILC. While our findings still require further validation, they may challenge current clinical practice and imaging modalities used in these patients. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect