A Human Fibroblast-Derived Growth Factor Preparation in the Management of a Chronic Surgical Wound in a Diabetic Patient: A Case Report

Autor: Angelo-Khattar M, Vadarli G
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: International Medical Case Reports Journal, Vol Volume 14, Pp 551-556 (2021)
Druh dokumentu: article
ISSN: 1179-142X
Popis: Maria Angelo-Khattar,1 Georgia Vadarli2 1American Academy of Anti-Aging Medicine (A4M), Dubai, United Arab Emirates; 2Consultant Plastic Surgeon, Thessaloniki, GreeceCorrespondence: Maria Angelo-KhattarAmerican Academy of Anti-Aging Medicine, Building 39, Dubai Healthcare City, Dubai, United Arab EmiratesTel +971506245494Email mkhattar@younatagroup.comAbstract: The treatment of choice in patients with ischaemic heart disease is coronary artery bypass grafting. The procedure entails the harvesting of the great saphenous vein through a significant leg incision, which may result in infections and wounding at the incision site. Patients with diabetes mellitus pose a greater risk of developing non-healing wounds, which may significantly affect the patient’s quality of life. The use of anti-inflammatory factors and other chemokines derived from cultured human fibroblasts may represent a useful therapeutic approach for the management of surgical wounds in patients with the greatest probability of being wound healing compromised. This case study describes the treatment of a non-healing surgical tibial wound in a male diabetic patient treated with a preparation of human anti-inflammatory interleukins cytokines, and growth factors. The treatment resulted in swift recovery, significant pain reduction and complete wound closure with minimal scarring.Keywords: chronic wound, growth factors, cytokines, coronary artery bypass graft
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