Comparative genomic sequencing to characterize Mycoplasma pneumoniae genome, typing, and drug resistance

Autor: Yue Jiang, Hailong Kang, Haiwei Dou, Dongxing Guo, Qing Yuan, Lili Dong, Zhenglin Du, Wenming Zhao, Deli Xin
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Microbiology Spectrum, Vol 12, Iss 8 (2024)
Druh dokumentu: article
ISSN: 2165-0497
DOI: 10.1128/spectrum.03615-23
Popis: ABSTRACT To analyze the characteristics of Mycoplasma pneumoniae as well as macrolide antibiotic resistance through whole-genome sequencing and comparative genomics. Thirteen clinical strains isolated from 2003 to 2019 were selected, 10 of which were resistant to erythromycin (MIC >64 µg/mL), including 8 P1-type I and 2 P1-type II. Three were sensitive (
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