| Autor: |
Rui-xue Ma, Lin-Feng Cheng, Qi-kang Ying, Rong-rong Liu, Tie-jun Ma, Xiao-xiao Zhang, Zi-yu Liu, Liang Zhang, Wei Ye, Fang-lin Zhang, Zhi-kai Xu, Fang Wang, Xing-an Wu |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2235-2988 |
| DOI: |
10.3389/fcimb.2016.00151 |
| Popis: |
The cytotoxic T lymphocyte (CTL) response plays a key role in controlling viral infection, but only a few epitopes within the HTNV glycoprotein (GP) that are recognized by CTLs have been reported. In this study, we identified one murine HTNV GP-derived H2-Kb-restricted CTL epitope in C57BL/6 mice, which could be used to design preclinical studies of vaccines for HTNV infection. First, 15 8-mer peptides were selected from the HTNV GP amino acid sequence based on a percentile rank of |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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