Incidence and Risk Factors of the Secondary Skin Infections in Patients with Radiodermatitis
| Autor: | Ulku Altoparlak, Ozlem Koca, Timur Koca |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Eurasian Journal of Medicine, Vol 43, Iss 03, Pp 177-181 (2011) |
| Druh dokumentu: | article |
| ISSN: | 1308-8734 1308-8742 |
| Popis: | Objective: The aim of this prospective study was to investigate the incidence and risk factors of secondary infected radiodermatitis in patients receiving radiotherapy and to determine isolated microorganisms’ resistance profiles to different antimicrobial agents.Materials and Methods: The study comprised 62 patients admitted to the Regional Training and Research Hospital from January 2009 to January 2010. Radiodermatitis was graded according to the National Cancer Institute’s Common Toxicity Criteria version 3.0. Potential risk factors for secondary infection were recorded and evaluated by univariate and multivariate analyses.Results: In 62 patients, grade 1, 2, 3 and 4 radiodermatitis were observed in 33 (53.2%), 11 (17.7%), 8 (12.9%) and 10 (16.2%) patients, respectively. Skin infection secondary to radiodermatitis occurred in 14 patients (infected patients), 21.4%, 21.4% and 57.2% of whom had grade 2, 3 and 4 radiodermatitis, respectively. Forty-eight patients were found to be colonized with micoorganisms (colonized patients). In the univariate analysis, concurrent endocrine therapy and radiodermatitis grade differed significantly between infected and colonized patients (p |
| Databáze: | Directory of Open Access Journals |
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