| Autor: |
Remco V. Klaassen, Jasper Stroeder, Françoise Coussen, Anne-Sophie Hafner, Jennifer D. Petersen, Cedric Renancio, Leanne J. M. Schmitz, Elisabeth Normand, Johannes C. Lodder, Diana C. Rotaru, Priyanka Rao-Ruiz, Sabine Spijker, Huibert D. Mansvelder, Daniel Choquet, August B. Smit |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms10682 |
| Popis: |
Auxiliary AMPA receptor subunits can affect gating and surface mobility. Here the authors show that Shisa6 traps AMPA receptors at postsynaptic sites via PSD-95, and keeps them in an activated state in the presence of glutamate, preventing full desensitization and consequently synaptic depression. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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