Optical Fiber-Based Module for Selection and Picking of Cells and Cell Clusters

Autor: Harish A. V., Varela Joao, Gibbon Timothy, Margulis Walter, Russom Aman, Laurell Fredrik
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: EPJ Web of Conferences, Vol 309, p 12007 (2024)
Druh dokumentu: article
ISSN: 2100-014X
DOI: 10.1051/epjconf/202430912007
Popis: We have developed an optical fiber-based module that can select, retrieve, and transfer single cells, and cell clusters. Cell picking and isolation has several applications such as separating circulating tumor cells, isolating single fetal cells for prenatal testing, and others. Our Lab-in-a-Fiber (LiF) module can detect fluorescent cancer cells (MCF-7) from a mixture of labeled and unlabeled cells and pick them up for further analysis. The cells picked up by the fiber show a 90% survival rate on viability tests, making this cell-picking technique an attractive alternative to existing methods.
Databáze: Directory of Open Access Journals