| Popis: |
Cerebral amyloid angiopathy associated with inflammation (CAA⁃I) is a rare subtype of cerebral amyloid angiopathy (CAA), and is increasingly recognized by neurologists. CAA⁃Iischaracterized by the pathological hallmarks of both CAA and vasculitis. The main clinical manifestations contain cognitive decline, seizures, headaches and so on, which present great clinical heterogeneity. Cranial MRI plays an important role in the diagnosis and evaluation of CAA⁃I, by which white matter hyperintensity (WMH) and multiple cerebral microbleeds (CMBs) could be usually found. CAA⁃I responds well to immunosuppressive therapy. All the characteristics above are different from CAA somehow. This paper aims to review the advances in pathophysiology, pathology, clinical manifestations, laboratory examination and treatment of CAA⁃I. DOI：10.3969/j.issn.1672⁃6731.2020.09.002 |
