In Vitro Assessment of Antileishmanial Activity of Natamycin and Nystatin

Autor: Arushdeep Sidana, Ajeet Kumar Negi, Umar Farooq
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Brazilian Archives of Biology and Technology, Vol 60, Iss 0 (2017)
Druh dokumentu: article
ISSN: 1678-4324
DOI: 10.1590/1678-4324-2017160368
Popis: ABSTRACT The present study was aimed to evaluate the in vitro antileishmanial activity of four different concentrations of natamycin and nystatin by using MTT 3-(4.5-dimethylthiazol-2-yl)-2.5-diphenyl tetrazolium bromide reduction assay. In vitro antileishmanial activity revealed that the IC50 of natamycin (80.49 μg/ml) and nystatin (105.7 μg/ml) was less than that of sodium stibogluconate (127.9 μg/ml), and more than amphotericin B (18.91 μg/ml).
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