Blainvillea rhomboidea: constituintes químicos e atividade citotóxica Blainvillea rhomboidea: chemical constituents and cytotoxic activity
| Autor: | Regina Ferreira Gomes, Hélcio Silva dos Santos, Maria Rose Jane R. Albuquerque, Otília Deusdênia L. Pessoa, Leticia V. Costa Lotufo, Claudia do Ó Pessoa, Manoel Odorico de Moraes, Felipe A. R. Rodrigues |
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| Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Química Nova, Vol 33, Iss 5, Pp 1122-1125 (2010) |
| Druh dokumentu: | article |
| ISSN: | 0100-4042 1678-7064 |
| DOI: | 10.1590/S0100-40422010000500022 |
| Popis: | The phytochemical investigation of the ethanol extract from the aerial parts of Blainvillea rhomboidea (Asteraceae) resulted in the isolation and characterization of 8β-tigloyloxy-grazielia acid, together with the flavonoids derrone, acacetin, luteolin and luteolin 7-methyl ether, and p-(1-methyl-ethan-1-ol)-phenol. The structures of all compounds were determined by spectroscopic methods (¹H and 13C NMR and HREIMS) and comparison with published spectral data. The flavonoids luteolin and 7-O-metyl-luteolin, isolated from the active dichloromethane fraction, showed moderate cytotoxic activity. |
| Databáze: | Directory of Open Access Journals |
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