The Ameliorative Effects of Phyllanthus gomphocarpus Hook. F. on Sperm Parameters of Rats Induced with Bisphenol A
| Autor: | Evana Kamarudin, Razif Dasiman, Ebby Anuar Bahari, Kamalru Azman Daud, Nur Rohmah Suwandi |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Majalah Obat Tradisional, Vol 28, Iss 3, Pp 197-206 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1410-5918 2406-9086 |
| DOI: | 10.22146/mot.84823 |
| Popis: | Infertility due to poor sperm quality is a common problem nowadays, particularly in developed countries. Herbs are one of the natural treatment options that have been proposed. Phyllanthus gomphocarpus Hook. F is a tropical plant that has traditionally been used in Malaysia to treat male infertility. Antioxidant characterization of its root aqueous extraction was performed using ferric reducing antioxidant power (FRAP), 1,1-diphenyl-2-picrylhydrazyl (DPPH), total phenolic content (TPC), and total flavonoid content (TFC). Male rats were administered two different concentrations of the extract orally along with BPA for 21 days, and their sperm was evaluated using Computer-Assisted-Sperm-Analysis (CASA). The results showed that this plant has a high antioxidant capacity, with 78.6 ± 0.65 %, 0.14 ± 0.01 mg/ml, 28.52 ± 0.13 mg GAE/g and 164.73 ± 23.13 mg QE/g, for DPPH, FRAP, TPC and TFC respectively. The ability of this plant to enhance sperm concentration, motility, velocity, progression ratio, elongation, and percentages of normal sperm morphology significantly with p |
| Databáze: | Directory of Open Access Journals |
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