ONE YEAR EXPERIENCE WITH INCLISIRAN IN AN ACADEMIC LIPID CLINIC

Autor: Tommy T. Chiou, BA, Kimberly Tomasi, RN, BSN, Pam R. Taub, MD, Michael J. Wilkinson, MD
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: American Journal of Preventive Cardiology, Vol 15, Iss , Pp 100567- (2023)
Druh dokumentu: article
ISSN: 2666-6677
DOI: 10.1016/j.ajpc.2023.100567
Popis: Therapeutic Area: Pharmacologic Therapy Background: Real-world data examining inclisiran use in US clinical practice are limited. We report a one-year experience with inclisiran in an academic lipid clinic. Methods: Retrospective chart review of patients prescribed inclisiran since FDA approval in December 2021. Results: 80 patients were prescribed inclisiran over 14 months (Table). Inclisiran was approved by insurance for 70 (88%) and denied for 10 (12%). 48 (60%) could not tolerate any statin as background lipid-lowering therapy (LLT). All patients with Medicare received approval for inclisiran, compared to 12 of 22 (55%) of non-Medicare patients. Approved patients were older (71±8 vs 59±15 years, p=0.004), disproportionately Medicare enrollees (83%, p
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