Extraskeletal Calcifications in Children with Maintenance Peritoneal Dialysis

Autor: Eunhye Oh, Jeesu Min, Seon Hee Lim, Ji Hyun Kim, Il-Soo Ha, Hee Gyung Kang, Yo Han Ahn
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Childhood Kidney Diseases, Vol 25, Iss 2, Pp 117-121 (2021)
Druh dokumentu: article
ISSN: 2384-0242
2384-0250
DOI: 10.3339/jkspn.2021.25.2.117
Popis: Chronic kidney disease (CKD)-mineral and bone disorder (CKD-MBD) is a common complication of CKD, often accompanied by extra-skeletal calcification in adult patients. As increased vascular calcification is predicted to increase cardiovascular mortality and morbidity, the revised Kidney Disease: Improving Global Outcomes guidelines recommend avoiding calcium-containing phosphate chelators. However, extra-skeletal calcification is less commonly noticed in pediatric patients. Here, we report our experience of such a complication in pediatric patients receiving maintenance peritoneal dialysis. Extra-skeletal calcification was noticed at the corneas, pelvic cavity, and soft tissues of the lower leg in 4 out of 32 patients on maintenance peritoneal dialysis. These patients experienced the aggravation of extra-skeletal calcifications during peritoneal dialysis, and 2 of them underwent excisional operations. It is required to monitor extra-skeletal calcifications in children on kidney replacement therapy.
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