Synthesis and fungicidal activity of novel imidazo[4, 5-b]pyridine derivatives

Autor: Wu Daoxin, Liu Minhua, Li Zhong, Dang Mingming, Liu Xingping, Li Jianming, Huang Lu, Ren Yeguo, Zhang Zai, Liu Weidong, Liu Aiping
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Heterocyclic Communications, Vol 25, Iss 1, Pp 8-14 (2019)
Druh dokumentu: article
ISSN: 2191-0197
DOI: 10.1515/hc-2019-0003
Popis: A series of novel imidazo[4,5-b]pyridine derivatives were synthesized and their structures were characterized by NMR spectroscopy, mass spectrometry and elemental analysis. The results of bioassays showed that some compounds exhibit good fungicidal activity against Puccinia polysora In particular, compound 7b showed an EC50 value of 4.00 mg/L, which was comparable with that of tebuconazole. Besides, preliminary structure-activity relationship was discussed.
Databáze: Directory of Open Access Journals