Comparative Study of the Efficacy of Topical Tranexamic Acid with Nasal Tampon in Management of Epistaxis: A Randomized Clinical Trial
| Autor: | Alireza Abootalebi Ghahnavieh, Abolfazl Tashayoie, Mohammad Nasr Esfahani, Keyhan Golshani |
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| Jazyk: | perština |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | مجله علمی دانشگاه علوم پزشکی کردستان, Vol 25, Iss 4, Pp 140-149 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1560-652X 2345-4040 |
| Popis: | Background and Aim: Epistaxis is one of the most common symptoms referring to emergency department, which suitable and effective treatment needs in short term. Therefore the purpose of the present study was to compare the outcome of topical tranexamic acid (TA) with nasal tampon in management of epistaxis. Materials and Methods: The present clinical trial study was performed on 150 patients with epistaxis in three groups. The patients of the first group were treated as a control group with a tampon that was lubricated with tetracycline ointment. The second group (TA group) received 15 cm gauze coated with TA and put in the nasal cavity. The third group received 15 cm gauze coated with TA and then nasal tampon coated with lubricant and tetracycline ointment. Then bleeding and nausea were assessed and recorded in the first 24 hours and the first week after intervention. Finally, statistical analysis was performed with SPSS software and Chi-square and one-way analysis of variance tests were used. Results: The time of bleeding cessation was significantly more in control groups as compared to intervention groups(P=0.04). The incidence of complications such as nausea and vomiting was much lower in the TA group than in the control group (P |
| Databáze: | Directory of Open Access Journals |
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