Design and Synthesis of Two Oxazine Derivatives Using Several Strategies
| Autor: | Figueroa-Valverde Lauro, Díaz-Cedillo Francisco, Rosas-Nexticapa Marcela, García-Cervera Elodia, Pool-Gómez Eduardo, López-Ramos María, Hau-Heredia Lenin, Sarabia-Alcocer Betty |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Journal of Chemistry, Vol 2014 (2014) |
| Druh dokumentu: | article |
| ISSN: | 2090-9063 2090-9071 |
| DOI: | 10.1155/2014/757953 |
| Popis: | Several oxazine derivatives have been synthesized; nevertheless, expensive reagents and special conditions are required. Therefore, in this study, two oxazine derivatives (2-chloro-3-{{2-[-(3-chloro-2-oxo-cyclobutyl)-(2,3-dimethoxy-9,10-dihydrostrychnid-10-yl)-amino]-ethyl}-[1,5-dimethyl-4-(1H-naphtho[1,2-e][1,3-oxazin-2-yl)-2-phenyl-2,3-dihydro-1H-pyrazol-3-yl]-amino}-cyclobutanone and 2-chloro-3-{{2-[(3-chloro-2-oxo-cyclobutyl)-(1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-amino]-ethyl}-[1,5-dimethyl-4-(1H-naphtho[1,2-e][1,3]oxazin-2-yl)-2-phenyl-2,3-dihydro-1H-pyrazol-3-yl]-amino}-cyclobutanone) were synthesized using several strategies. The structure of compounds obtained was confirmed by elemental analysis, spectroscopy, and spectrometry data. In conclusion, the methods used offer some advantages such as good yields, simple procedure, low cost, and ease of workup. |
| Databáze: | Directory of Open Access Journals |
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