Improving Outcomes of Same-sitting Bilateral Flexible Ureteroscopy for Renal Stones in Real-world Practice—Lessons Learnt from Global Multicenter Experience of 1250 Patients

Autor: Daniele Castellani, Olivier Traxer, Deepak Ragoori, Andrea Benedetto Galosi, Virgilio De Stefano, Nariman Gadzhiev, Yiloren Tanidir, Takaaki Inoue, Esteban Emiliani, Saeed Bin Hamri, Mohamed Amine Lakmichi, Chandra Mohan Vaddi, Chin Tiong Heng, Boyke Soebhali, Sumit More, Vikram Sridharan, Mehmet Ilker Gökce, Azimdjon N. Tursunkulov, Arvind Ganpule, Giacomo Maria Pirola, Angelo Naselli, Cemil Aydin, Fernando Ramón de Fata Chillón, Catalina Solano Mendoza, Luigi Candela, Ben Hall Chew, Bhaskar Kumar Somani, Vineet Gauhar
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: European Urology Open Science, Vol 52, Iss , Pp 51-59 (2023)
Druh dokumentu: article
ISSN: 2666-1683
DOI: 10.1016/j.euros.2023.03.018
Popis: Background: Bilateral kidney stones are commonly treated in staged procedures. Objective: To evaluate outcomes after same-sitting bilateral retrograde intrarenal surgery (SSB-RIRS) for renal stones. Design, setting, and participants: Data from adults who underwent bilateral RIRS in 21 centers were retrospectively reviewed (from January 2015 to June 2022). The inclusion criteria were unilateral/bilateral symptomatic bilateral stone(s) of any size/location in both kidneys and bilateral stones on follow-up with symptom/stone progression. Stone-free rate (SFR) was defined as absence of any fragment >3 mm at 3 mo. Outcome measurements and statistical analysis: Continuous variables are presented as medians and 25–75th percentiles. A multivariable logistic regression analysis was performed to evaluate independent predictors of sepsis and bilateral SFR. Results and limitations: A total of 1250 patients were included. The median age was 48.0 (36–61) yr. Of the patients, 58.2% were prestented. The median stone diameter was 10 mm on both sides. Multiple stones were present in 45.3% and 47.9% of the left and right kidneys, respectively. Surgery was stopped in 6.8% of cases. The median surgical time was 75.0 (55–90) min. Complications were transient fever (10.7%), fever/infection needing prolonged stay (5.5%), sepsis (2%), and blood transfusion (1.3%). Bilateral and unilateral SFRs were 73.0% and 17.4%, respectively. Female (odds ratio [OR] 2.97, 95% confidence interval [CI] 1.18–7.49, p = 0.02), no antibiotic prophylaxis (OR 5.99, 95% CI 2.28–15.73, p
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