Generation of iPS cell lines from schizophrenia patients using a non-integrative method
| Autor: | Jaroslaw Sochacki, Sylvie Devalle, Marcelo Reis, Renata de Moraes Maciel, Bruna da Silveira Paulsen, Helena Brentani, Paulo Silva Belmonte-de-Abreu, Stevens Rehen |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Stem Cell Research, Vol 17, Iss 1, Pp 97-101 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1873-5061 1876-7753 |
| DOI: | 10.1016/j.scr.2016.05.017 |
| Popis: | Skin biopsies were collected from three male patients (age 45, 44 and 44) with clinically diagnosed schizophrenia. The patients were diagnosed according to DSM-5 criteria by a trained psychiatrist. Dermal fibroblast cell lines were established and expanded for subsequent reprogramming procedures. Induced pluripotent stem (iPS) cells were derived using the integration-free CytoTune®-iPS 2.0 Sendai Reprogramming Kit, containing Sendai virus particles of the four Yamanaka factors Oct3/4, Sox2, Klf4 and c-Myc. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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