Validating a clinical prediction score for Legionella-related community acquired pneumonia

Autor: Rosalie R. A. L. Beekman, Ruud R. Duijkers, Dominic D. Snijders, Menno M. van der Eerden, Martijn M. Kross, Wim W. G. Boersma
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-8 (2022)
Druh dokumentu: article
ISSN: 1471-2334
DOI: 10.1186/s12879-022-07433-z
Popis: Abstract Background Legionella-related community acquired pneumonia (CAP) is a disease with an increasing incidence and a high mortality rate, especially if empirical antibiotic therapy is inadequate. Antibiotic treatment highly relies on clinical symptoms, although proven non-specific, because currently available diagnostic techniques provide insufficient accuracy for detecting Legionella CAP on admission. This study validates a diagnostic scoring system for detection of Legionella-related CAP, based on six items on admission (Legionella prediction score). Methods We included patients with Legionella-related CAP admitted to five large Dutch hospitals between 2006 and 2016. Controls were non-Legionella-related CAP patients. The following six conditions were rewarded one point if present: fever > 39.4 °C; dry cough; hyponatremia (sodium) 225 mmol/L; C-reactive protein (CRP) > 187 mg/L and platelet count
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje