SPf66 vaccine trial in Brazil: conceptual framework study design and analytical approach

Autor: M. Urdaneta, A. Prata, C.J. Struchiner, C.E. Tosta, P. Tauil, M. Boulos
Jazyk: angličtina
Rok vydání: 1996
Předmět:
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical, Vol 29, Iss 3, Pp 259-269 (1996)
Druh dokumentu: article
ISSN: 1678-9849
0037-8682
DOI: 10.1590/S0037-86821996000300007
Popis: This paper describes the study population and the study design of the phase III field trial of the SPf66 vaccine in Brazil. Assessment of validity and precision principles necessary for the appropriate evaluation of the protective effect of the vaccine are discussed, as well as the results of the preliminary analyses of the gathered data. The analytical approach for the estimation of the protective effect of the vaccine is presented. This paper provides the conceptual framework for future publications.
Databáze: Directory of Open Access Journals