COVID-19 and thrombotic complications—the role of anticoagulants, antiplatelets and thrombolytics

Autor: Gaurav Khandelwal, Avik Ray, Samdish Sethi, H K Harikrishnan, Chaitanya Khandelwal, Balakrishnan Sadasivam
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Family Medicine and Primary Care, Vol 10, Iss 10, Pp 3561-3567 (2021)
Druh dokumentu: article
ISSN: 2249-4863
DOI: 10.4103/jfmpc.jfmpc_1297_20
Popis: Coronavirus disease 2019 (COVID-19) is a global pandemic the world is dealing with currently. Clinical evidences suggest that the patients are predisposed to both venous and arterial thrombotic complications. This is because of severe inflammatory responses, injury to endothelium and activation of platelets leading to increased coagulation. Additionally, individuals who are already receiving antithrombotic drug therapy for various cardiovascular diseases and complications might contract the disease in which case, attention should be given to the choice and duration of the therapy besides close monitoring of biochemical blood parameters. Herein, we review the incidences of thrombotic complications and their outcomes in COVID-19 patients as reported till date, while understanding the prophylactic and therapeutic roles of anticoagulants, antiplatelets and thrombolytics in the management of this severe viral respiratory illness.
Databáze: Directory of Open Access Journals
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