Delayed presentation is associated with serious bacterial infections among febrile infants: A prospective cohort study

Autor: Karthigha Pon Rajoo, Natalia Sutiman, Stephanie Shih, Zi Xean Khoo, Gene Yong-Kwang Ong, Lena Won, Rupini Piragasam, Sashikumar Ganapathy, Shu-Ling Chong
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Annals, Academy of Medicine, Singapore, Vol 53, Iss 5, Pp 286-292 (2024)
Druh dokumentu: article
ISSN: 2972-4066
DOI: 10.47102/annals-acadmedsg.2023350
Popis: Introduction: Febrile young infants are at risk of serious bacterial infections (SBIs), which are potentially life-threatening. This study aims to investigate the association between delayed presentation and the risk of SBIs among febrile infants. Method: We performed a prospective cohort study on febrile infants ≤90 days old presenting to a Singapore paediatric emergency department (ED) between November 2017 and July 2022. We defined delayed presentation as presentation to the ED >24 hours from fever onset. We compared the proportion of SBIs in infants who had delayed presentation compared to those without, and their clinical outcomes. We also performed a multivariable logistic regression to study if delayed presentation was independently associated with the presence of SBIs. Results: Among 1911 febrile infants analysed, 198 infants (10%) had delayed presentation. Febrile infants with delayed presentation were more likely to have SBIs (28.8% versus [vs] 16.3%, P
Databáze: Directory of Open Access Journals