Pneumocystis Pneumonia and Acute Kidney Injury Induced by Everolimus Treatment in a Patient with Metastatic Breast Cancer

Autor: Mayuko Nakamura, Ryoichi Matsunuma, Kei Yamaguchi, Ryosuke Hayami, Michiko Tsuneizumi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Case Reports in Oncology, Vol 13, Iss 1, Pp 170-175 (2020)
Druh dokumentu: article
ISSN: 1662-6575
DOI: 10.1159/000505909
Popis: Everolimus, an inhibitor of the rapamycin pathway, is administered with the combination of an aromatase inhibitor for the treatment of metastatic estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative breast cancers. Interstitial lung disease is a well-known major adverse event associated with everolimus treatment, but it is often difficult to distinguish between interstitial lung disease and Pneumocystis pneumonia, a lung infection. Acute kidney injury is another adverse event that is associated with everolimus use. In this article, we report a case of Pneumocystis pneumonia without respiratory symptoms and acute kidney injury induced by everolimus treatment in a patient with ER-positive and HER2-negative metastatic breast cancer.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje