Unsuspected Dengue and Acute Febrile Illness in Rural and Semi-Urban Southern Sri Lanka

Autor: Megan E. Reller, Champika Bodinayake, Ajith Nagahawatte, Vasantha Devasiri, Wasantha Kodikara-Arachichi, John J. Strouse, Anne Broadwater, Truls Østbye, Aravinda de Silva, Christopher W. Woods
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 18, Iss 2, Pp 256-263 (2012)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid1802.110962
Popis: Dengue virus (DENV), a globally emerging cause of undifferentiated fever, has been documented in the heavily urbanized western coast of Sri Lanka since the 1960s. New areas of Sri Lanka are now being affected, and the reported number and severity of cases have increased. To study emerging DENV in southern Sri Lanka, we obtained epidemiologic and clinical data and acute- and convalescent-phase serum samples from patients >2 years old with febrile illness. We tested paired serum samples for DENV IgG and IgM and serotyped virus by using isolation and reverse transcription PCR. We identified acute DENV infection (serotypes 2, 3, and 4) in 54 (6.3%) of 859 patients. Only 14% of patients had clinically suspected dengue; however, 54% had serologically confirmed acute or past DENV infection. DENV is a major and largely unrecognized cause of fever in southern Sri Lanka, especially in young adults.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje