Pemphigus Vulgaris in Old Patient

Autor: Bassel Tarakji
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Case Reports in Dentistry, Vol 2021 (2021)
Druh dokumentu: article
ISSN: 2090-6447
2090-6455
DOI: 10.1155/2021/3946161
Popis: Pemphigus vulgaris (PV) is a chronic, autoimmune, intraepidermal blistering disease of the skin and mucous membranes. The first clinical manifestation is often the development of intraoral lesions, and later, the lesions involve the other mucous membranes and skin. The etiological factors of this disease still remain unknown, although the presence of autoantibodies is consistent with an autoimmune disease. A 73-year-old man had bullous lesions on gingiva, oral mucosa first, then scalp, trunk, and face. An oral medicine specialist suspects the lesion in differential diagnosis in the first presentation of oral lesions and follows up the patient, and then these bullous lesions presented on the skin. In this article, a patient had received oral prednisolone (80 mg/kg/day) and azathioprine, then tapered oral prednisolone to 40 mg/day, with a reduction of 5 mg/day every three weeks. The patient shows remission of these lesions, and complication of this treatment includes osteoporosis, hyperglycemia, and hypertension.
Databáze: Directory of Open Access Journals