Non invasive assessment of liver fibrosis in chronic hemodialysis patients with viral hepatitis C

Autor: Mohamed Arrayhani, Tarik Sqalli, Nada Tazi, Randa El Youbi, Safae Chaouch, Nourdin Aqodad, Sidi Adil Ibrahimi
Jazyk: English<br />French
Rok vydání: 2015
Předmět:
Zdroj: The Pan African Medical Journal, Vol 22, Iss 273 (2015)
Druh dokumentu: article
ISSN: 1937-8688
DOI: 10.11604/pamj.2015.22.273.2311
Popis: The liver biopsy has long been the "gold standard" for assessing liver fibrosis in patients with hepatitis C. It's an invasive procedure which is associated with an elevated bleeding, especially in chronic hemodialysis patients. Main goal is to assess liver fibrosis in chronic hemodialysis with HCV by Fibroscan and by biological scores (APRI, Forns and Fib-4), and to measure the correlation between these tests. Cross-sectional study including all chronic hemodialysis patients with hepatitis C virus, in two public hemodialysis centers of Fez. All patients were evaluated for liver fibrosis using noninvasive methods (FibroScan and laboratory tests). Subsequently, the correlation between different tests has been measured. 95 chronic hemodialysis were studied, twenty nine patients (30.5%) with chronic hepatitis C. The average age was 52.38 ; 16.8 years. Nine liver fibrosis cases have been concluded by forns score. Fibroscan has objectified significant fibrosis in 6 cases. On the other side APRI has objectified sgnifivant fibrosis only in 3 cases. The Fib-4 showed severe fibrosis in five cases. The results have been most consistent between APRI and Fib-4, followed by Fibroscan and Forns, then APRI and FibroScan.
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