Assessment of the FreeStyle Libre 2 interstitial glucose monitor in hypo‐ and euglycemic cats

Autor: Alisa S. Berg, Chiquitha D. Crews, Christopher Adin, Adriana Alfonso‐Castro, Susan B. Hill, Jocelyn Mott, Chen Gilor
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Veterinary Internal Medicine, Vol 37, Iss 5, Pp 1703-1709 (2023)
Druh dokumentu: article
ISSN: 1939-1676
0891-6640
DOI: 10.1111/jvim.16820
Popis: Abstract Background Continuous glucose monitoring systems have been validated for eu‐ and hyperglycemic cats. The FreeStyle Libre 2 (FSL2) is sufficiently accurate in people during hypoglycemia to guide critical treatment decisions without confirmation of blood glucose concentration (BG). Objectives Assess FSL2 accuracy in cats with hypoglycemia. Animals Nine healthy, purpose‐bred cats. Methods Hyperinsulinemic‐hypoglycemic clamps were performed by IV infusion of regular insulin (constant rate) and glucose (variable rate). Interstitial glucose concentration (IG), measured by FSL2, was compared to BG measured by AlphaTrak2. Data were analyzed for all paired measurements (n = 364) and separately during stable BG (≤1 mg/dL/min change over 10 minutes). Pearson's r test, Bland‐Altman test, and Parkes Error Grid analysis respectively were used to determine correlation, bias, and clinical accuracy (P
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