| Autor: |
Ingrid White, Dualta McQuaid, Helen McNair, Alex Dunlop, Steven Court, Naomi Hopkins, Karen Thomas, David Dearnaley, Shree Bhide, Susan Lalondrelle |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Physics and Imaging in Radiation Oncology, Vol 9, Iss , Pp 97-102 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2405-6316 |
| DOI: |
10.1016/j.phro.2019.02.005 |
| Popis: |
Background and purpose: Appropriate internal margins are essential to avoid a geographical miss in intensity-modulated radiation therapy (IMRT) for endometrial cancer (EC). This study evaluated interfraction target motion using rigid and non-rigid approximation strategies and calculated internal margins based on random and systematic errors using traditional rigid margin recipes. Dosimetric impact of target motion was also investigated. Materials and methods: Cone beam CTs (CBCTs) were acquired days 1–4 and then weekly in 17 patients receiving adjuvant IMRT for EC; a total of 169 CBCTs were analysed. Interfraction motion for the clinical target volume vaginal vault and upper vagina (CTVv) was measured using bony landmarks and deformation vector field displacement (DVFD) within a 1 mm internal wall of CTVv. Patient and population systematic and random errors were estimated and margins calculated. Delivered dose to the CTVv and organs at risk was estimated. Results: There was a significant difference in target motion assessment using the different registration strategies (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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