Programming a topologically constrained DNA nanostructure into a sensor

Autor: Meng Liu, Qiang Zhang, Zhongping Li, Jimmy Gu, John D. Brennan, Yingfu Li
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms12074
Popis: DNA nanostructures with interlocked topologies will tend to display different behaviour to the linear counterparts. Here, the authors show a DNA catenane that is inactive for rolling circle amplification but is activated upon cleavage of one ring, and exploit this for the development of a biosensing system.
Databáze: Directory of Open Access Journals