Copper catalyzed late-stage C(sp3)-H functionalization of nitrogen heterocycles

Autor: Zhe Chang, Jialin Huang, Si Wang, Geshuyi Chen, Heng Zhao, Rui Wang, Depeng Zhao
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-24671-y
Popis: Late-stage C(sp3)-H bond functionalization of N-heterocycles with broad substrate scope remains a challenge and of particular significance to modern chemical synthesis and pharmaceutical chemistry. Here the authors show copper-catalysed late-stage C(sp3)-H functionalizaion of N-heterocycles using commercially available catalysts under mild reaction conditions.
Databáze: Directory of Open Access Journals