Protective effects of Resveratrol in an experimental model of abdominal aortic aneurysm induction
| Autor: | D. Palmieri, C. Barisione, C, Pane, G. Spinella, S. Garibaldi, G. Ghigliotti, C. Brunelli, E. Fulcheri, D. Palombo |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Journal of Biological Research, Vol 84, Iss 1 (2011) |
| Druh dokumentu: | article |
| ISSN: | 1826-8838 2284-0230 |
| DOI: | 10.4081/jbr.2011.4638 |
| Popis: | Resveratrol (Rsv) is a natural antioxidant polyphenol with vasoprotective properties. We evaluated whether Rsv affects the inflammatory response in an experimental model of elastase-induced abdominal aortic aneurysm. Thirty male rats were subjected to aneurysm induction and treated or not with Rsv. Circulating levels of CD62L-monocyte subset, monocyte CD I 43 surface expression, MMP-9 plasma activity and TNFα serum levels were lower in Rsv-treated rats. In conclusion. Rsv acts as an anti-inflammatory compound and could be of great revelance to improve the immune response in AAA patients. |
| Databáze: | Directory of Open Access Journals |
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