Antiplasmodial and in vitro antioxidant potentials of crude aqueous and methanol extracts of Chasmanthera dependens (Hochst)

Autor: Conrad Kenechukwu Enenebeaku, Cynthia Ekwy Ogukwe, Christian Okechukwu Nweke, Sylvia Onyinyechi Anyado-Nwadike, Martin Obi, Ijeoma Akunna Duru, Uchechi Emmanuela Enenebeaku, Odangowei I. Ogidi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Bulletin of the National Research Centre, Vol 46, Iss 1, Pp 1-12 (2022)
Druh dokumentu: article
ISSN: 2522-8307
DOI: 10.1186/s42269-022-00721-3
Popis: Abstract Background Malaria is a major cause of death in tropical countries such as Nigeria. Chasmanthera dependens (Hochst) is a wild plant used by traditional healers for the treatment of malaria and other health challenges. This study evaluated the 'Antiplasmodial and in vitro antioxidant potentials of crude aqueous and methanol extracts of leaves, root and stem of Chasmanthera dependens (Hochst)’. Results Methanol extracts of leaves and roots of this plant exhibited higher antimalarial activities than other extracts. The level of parasitemia was significantly (p
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