| Autor: |
Maroussia Roelens, Alexis Martin, Brian Friker, Filipe Maximiano Sousa, Amaury Thiabaud, Beatriz Vidondo, Valentin Buchter, Céline Gardiol, Jasmin Vonlanthen, Carlo Balmelli, Manuel Battegay, Christoph Berger, Michael Buettcher, Alexia Cusini, Domenica Flury, Ulrich Heininger, Anita Niederer-Loher, Thomas Riedel, Peter W. Schreiber, Rami Sommerstein, Nicolas Troillet, Sarah Tschudin-Sutter, Pauline Vetter, Sara Bernhard-Stirnemann, Natascia Corti, Roman Gaudenz, Jonas Marschall, Yvonne Nussbaumer-Ochsner, Laurence Senn, Danielle Vuichard-Gysin, Petra Zimmermann, Franziska Zucol, Anne Iten, Olivia Keiser |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Swiss Medical Weekly, Vol 151, Iss 4748 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1424-3997 |
| DOI: |
10.4414/SMW.2021.w30105 |
| Popis: |
BACKGROUND: When the periods of time during and after the first wave of the ongoing SARS-CoV-2/COVID-19 pandemic in Europe are compared, the associated COVID-19 mortality seems to have decreased substantially. Various factors could explain this trend, including changes in demographic characteristics of infected persons and the improvement of case management. To date, no study has been performed to investigate the evolution of COVID-19 in-hospital mortality in Switzerland, while also accounting for risk factors. METHODS: We investigated the trends in COVID-19-related mortality (in-hospital and in-intermediate/intensive-care) over time in Switzerland, from February 2020 to June 2021, comparing in particular the first and the second wave. We used data from the COVID-19 Hospital-based Surveillance (CH-SUR) database. We performed survival analyses adjusting for well-known risk factors of COVID-19 mortality (age, sex and comorbidities) and accounting for competing risk. RESULTS: Our analysis included 16,984 patients recorded in CH-SUR, with 2201 reported deaths due to COVID-19 (13.0%). We found that overall in-hospital mortality was lower during the second wave of COVID-19 than in the first wave (hazard ratio [HR] 0.70, 95% confidence interval [CI] 0.63– 0.78; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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