Autor: |
Wen-Xuan Yu, Christina Chui-Wa Poon, Li-Ping Zhou, Ka-Ying Wong, Si-Si Cao, Chung-Yan Lam, Wayne Yuk-wai Lee, Man-Sau Wong |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116402- (2024) |
Druh dokumentu: |
article |
ISSN: |
0753-3322 |
DOI: |
10.1016/j.biopha.2024.116402 |
Popis: |
Oleanolic acid (OA) is previously shown to exert bone protective effects in aged animals. However, its role in regulating osteoblastic vitamin D bioactivation, which is one of major causes of age-related bone loss, remains unclear. Our results revealed that treatment of OA significantly increased skeletal CYP27B1 expression and circulating 1,25(OH)2D3 in ovariectomized mice (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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