Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022

Autor: Hanna Vauhkonen, Hannimari Kallio-Kokko, Eija Hiltunen-Back, Lasse Lönnqvist, Jaana Leppäaho-Lakka, Laura Mannonen, Ravi Kant, Tarja Sironen, Satu Kurkela, Maija Lappalainen, Tomaž Mark Zorec, Samo Zakotnik, Doroteja Vlaj, Miša Korva, Tatjana Avšič-Županc, Mario Poljak, Teemu Smura, Olli Vapalahti
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 29, Iss 3, Pp 649-652 (2023)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid2903.221388
Popis: Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–mediated evolution or co-infection.
Databáze: Directory of Open Access Journals