Benchmarking integration of single-cell differential expression

Autor: Hai C. T. Nguyen, Bukyung Baik, Sora Yoon, Taesung Park, Dougu Nam
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-37126-3
Popis: Integration of single-cell RNA sequencing data between different samples has been a major challenge for analyzing cell populations. Here the authors benchmark 46 workflows for differential expression analysis of single-cell data with multiple batches and suggest several high-performance methods under different conditions based on simulation and real data analyses.
Databáze: Directory of Open Access Journals