| Autor: |
Saurabh Dey, Bini Biswas, Sangeeta Ballav, Vishal Kumar Sahu, Amit Ranjan, Soumya Basu |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Food Chemistry Advances, Vol 2, Iss , Pp 100321- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2772-753X |
| DOI: |
10.1016/j.focha.2023.100321 |
| Popis: |
Non-coding RNA (ncRNAs) is greatly known to be involved in many cellular processes such as growth and development including tumorigenesis. Alterations in expression of ncRNAs are observed in several cancers. Therefore, they are regarded as potential players in carcinogenesis. In a broader view, it has been documented that ncRNAs are also involved in hormone-associated cancers (HACs) by regulating their epigenetic processes. Hence, HACs emerge on the radar of scientific community and cancer research as they are widely influenced by hormone levels and latter promotes cancer growth. Although various risk factors point to HACs, findings are inconsistent and not uniform. Dietary flavonoids are amongst the natural compounds that are capable of repressing the proliferation and growth of numerous cancer cells. This could be rewarding and might open new avenues for cancer treatment. In addition, flavonoids seem to have anti-hormone like properties in HACs. However, there are no direct assessment of flavonoids and their effects in HACs. The studies are not stringent enough to evaluate the intake of these dietary flavonoids. Herein, the present review highlights the role of numerous dietary flavonoids as ncRNA modulators in HACs. Mechanisms of ncRNA regulation and the role of hormones associated with hormone-specific cancer has also been discussed. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
