PD‐L1 on large extracellular vesicles is a predictive biomarker for therapy response in tissue PD‐L1‐low and ‐negative patients with non‐small cell lung cancer

Autor: Nadja Schöne, Marcel Kemper, Kerstin Menck, Georg Evers, Carolin Krekeler, Arik Bernard Schulze, Georg Lenz, Eva Wardelmann, Claudia Binder, Annalen Bleckmann
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Extracellular Vesicles, Vol 13, Iss 3, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2001-3078
DOI: 10.1002/jev2.12418
Popis: Abstract Immunotherapy has revolutionized the treatment of patients with non‐small cell lung cancer (NSCLC). High expression of tissue PD‐L1 (tPD‐L1) is currently the only approved biomarker for predicting treatment response. However, even tPD‐L1 low (1‐49%) and absent (
Databáze: Directory of Open Access Journals
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