Cystatin-C and TGF-β levels in patients with diabetic nephropathy
| Autor: | Mumtaz Takir, Aslı Dogruk Unal, Osman Kostek, Nilufer Bayraktar, Nilgun Guvener Demirag |
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| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Nefrología, Vol 36, Iss 6, Pp 653-659 (2016) |
| Druh dokumentu: | article |
| ISSN: | 0211-6995 42154332 |
| DOI: | 10.1016/j.nefro.2016.06.011 |
| Popis: | Objective: To evaluate renal impairment in type 2 diabetic patients with normoalbuminuria or microalbuminuria by detection of serum cystatin C and serum and urinary TGF-β levels. Methods: Cross-sectional study conducted at the Department of Endocrinology in Baskent University School of Medicine. Patients with type 2 diabetes mellitus without known overt diabetic nephropathy were included in the study. Recruited patients were stratified into four groups, matched in terms of age, gender, microalbuminuria level and estimated GFR calculated with MDRD. Results: 78 patients were enrolled. They were categorized into four groups depending on their urinary albumin excretion and estimated glomerular filtration rate. Macrovascular complication was found to be higher in patients with microalbuminuria than in other patients (p |
| Databáze: | Directory of Open Access Journals |
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