| Autor: |
Begoña López, Maria Castañón-Apilánez, Javier Molina-Gil, Santiago Fernández-Gordón Sánchez, Gemma González, Antía Reguera Acuña, Jose Maria Jimenez, Davinia Larrosa Campo, Montserrat González Delgado, Lorena Benavente-Fernández, Maria Rico-Santos, Carmen García-Cabo, Sergio Calleja Puerta, Elena López-Cancio |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Cerebrovascular Diseases Extra (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1664-5456 |
| DOI: |
10.1159/000526354 |
| Popis: |
Background: Prealbumin is a marker of malnutrition and inflammation. It has been associated with poor prognosis in cardiovascular disease, but less is known in stroke patients. Our objective was to evaluate the association of prealbumin levels at admission with prognosis in patients with stroke treated with mechanical thrombectomy. Material & Methods: Retrospective study of a prospective database of consecutive patients treated with mechanical thrombectomy. Clinical, radiological and blood parameters including serum prealbumin, and prognostic variables such as respiratory infection, in-hospital mortality, and modified Rankin scale at 3 months were collected. Results: We included 319 patients between 2018-2019. Prealbumin levels were significantly lower in patients older than 80 years, women, patients with a prestroke Rankin score >2, glomerular filtrate rate 2), in-hospital mortality and 3-month mortality. In multivariate analysis, prealbumin was an independent risk factor associated with mortality at 3 months, OR 0.92 [0.86-0.98], p = 0.019. Conclusion: Lower prealbumin levels at admission behaved as independent predictor of long-term mortality in patients treated with mechanical thrombectomy. These results should be replicated in other cohorts. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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