| Autor: |
Haiying Wang, Jian Tong, Yi Cao |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Radiation Medicine and Protection, Vol 5, Iss 2, Pp 68-74 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2666-5557 |
| DOI: |
10.1016/j.radmp.2024.04.002 |
| Popis: |
Cellular senescence has emerged as an important contributor to aging and age-related diseases. Non-ionizing radiation (NIR), including ultraviolet radiation and electromagnetic fields, has been increasingly recognized as a key inducer of premature senescence. In this review, we discuss the molecular mechanisms of NIR-induced cellular senescence and its effects on aging and age-related diseases. We also summarize the modulation strategies for NIR-induced cellular senescence. A better understanding of the complex relationship between non-ionizing radiation, cellular senescence and age-related pathology may lead to interventions to ameliorate radiation damage and delay aging. Further research is still needed to elucidate the precise mechanisms, dose-response effects, and to develop protective strategies against radiation-induced senescence. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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