Clinical and echocardiographic characteristics of patients with atrial cardiomyopathy and their impact on prognosis

Autor: Radostina Ilieva, Elena Kinova, Boris Slavchev, Petar Kalaydzhiev, Desislava Somleva, Assen Goudev
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Folia Medica, Vol 66, Iss 5, Pp 608-617 (2024)
Druh dokumentu: article
ISSN: 1314-2143
DOI: 10.3897/folmed.66.e135893
Popis: Introduction: Patients with diverse demographic and clinical characteristics and comorbidities are included in the category of atrial cardiomyopathy (ACM). Aim: Our study aims to evaluate the demographic, clinical, laboratory, and echocardiographic parameters of patients with ACM and to assess their impact on prognosis. Materials and methods: Only 200 of the 724 consecutively evaluated patients with dilated left atrium who met the criteria for advanced ACM were included in the analysis. Forty age- and sex-matched controls with normal left atrial volume were also included. On enrollment, all patients received a detailed echocardiography with volumetric and speckle tracking analysis, and they were followed for 36 months for cardiovascular outcomes, including mortality. Results: The mean age of the ACM population was 73.91±9.74 years, with 58% being women. Hypertension was found in 93% of them, 79% had atrial fibrillation, 60% had heart failure, 37% were obese, and 26% had diabetes. Over a median follow-up of 20.6 months, 35 deaths were registered in the ACM group compared to 1 death in the control group (17.5% vs. 2%, p=0.011). The presence of heart failure (HR 5.2, p=0.004), cancer (HR 3.7, p=0.007), severe tricuspid regurgitation (TR) (HR 5.4, p−17 %.
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